Endocrine Abstracts

Section 1: Case history: A 55 year old female patient sought review from her GP due to ongoing fatigue, muscle weakness, scalp hair thinning, weight gain and fluid retention. This had been ongoing for a few months and she was started on HRT. Initially she saw an improvement however her relief from symptoms was short lived. 5 months later she noticed a rash which was described as purpuric. A relative described her as having a “moon face” which prompted further review ...

Introduction: The current UK guidelines (NICE TA791) recommend the use of romosozumab, a monoclonal sclerostin inhibitor, for patients at high imminent risk of fragility fractures. However, elderly patients with a very high risk of fractures often exhibit frailty and other comorbidities. This retrospective survey was conducted in a major trauma centre in northern England to evaluate the potential utilisation of romosozumab in a real-world setting.<p class=...

Introduction: Women with PCOS have a higher risk of metabolic syndrome and cardiovascular complications. We aimed to understand if routinely measured hormonal parameters can identify women with PCOS with a higher risk of metabolic syndrome (MetS).Methods: The data for the study consisted of a discovery cohort (PCOS clinic database) and a replication cohort (Hull PCOS Biobank.) We used eight routinely measured hormonal parameters in our clinics (free andr...